HORIZON 2020 Societal Challenges Sustainable Food Security Assessing the health risks of combined human exposure to multiple food-related toxic substances

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Budget: €128,000,000 H2020-SFS-2014-2
Deadline Date: 12-03-2014
Deadline Date Stage 2: 26-06-2014
Programme: Horizon 2020
MAX Co-funding rate: 100
Applicants: Research centres, Local and Regional authorities, SME
Regions: European Union, Candidate countries, European Economic Area
Eligibility conditions: Three legal entities. Each of the three shall be established in a different Member State or associated country. All three legal entities shall be independent of each other.
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The state-of-the-art frameworks already in place at international level should be reviewed in the quest for a harmonised, evidence- and risk-based approach. Proposals should focus on the health risks of combined exposures to multiple chemicals from multiple sources across differing life stages, while weighing the risks from chemical mixtures in diets against the health benefits from the same foods and taking into account also the gender dimension. New strategies should be developed, implemented and supported by the respectively developed software and databases and tested in operational environments – using, for example, ‘omics’ technologies, bioassay systems, mathematical modelling, quantitative structure-activity relationship models and threshold of toxicological concern – so that tiered approaches for testing can be followed and targeted testing protocols developed. Proposals should address responsible research and innovation aspects by developing strategies that will result in a reduction in the use of animals in toxicological research.
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