Nanomedicine therapy for cancer
Specific challenge:Promising pre-clinical nano-medicine proof-of-concepts have been developed for the therapy of cancer, but their translation into clinical therapies remains a major challenge.
Biomaterials for treatment and prevention of Alzheimer
Specific challenge:An estimated 7.
HORIZON 2020 Health Co-ordination Activities Support for European Reference Networks: efficient network modelling and validation
HORIZON 2020 Health Co-ordination Activities Global Alliance for Chronic Diseases. Prevention and treatment of lung diseases
Specific challenge: The Global Alliance for Chronic Diseases will focus its 2015 call for implementation science proposals on lung diseases.
HORIZON 2020 Health Co-ordination Activities ERA NET Collaboration and alignment of national programmes and activities in the area of brain-related diseases and disorders of the nervous system
Specific challenge:The challenges in the areas of brain-related diseases can only be met by an effective cooperation at transnational level avoiding the duplication of efforts, ensuring the availability of critical mass, efficiently using available resources, exchanging knowledge, producing more significant results of higher quality and impact, and sharing data and infrastructures.
HORIZON 2020 Health Co-ordination Activities ERA NET: Antimicrobial resistance
Specific challenge:Antibiotic resistance is a global problem.
HORIZON 2020 Health Co-ordination Activities ERA-NET: Cardiovascular disease
Specific challenge: Cardiovascular diseases (CVD) are the largest cause of death in the EU and account for 40% of deaths or 2 million deaths per year.
HORIZON 2020 PERSONALISING HEALTH AND CARE Understanding disease: systems medicine
Specific challenge:The development of new, evidence-based treatments relies on an improved understanding of the often very complex pathophysiology of diseases.
HORIZON 2020 Health Co-ordination Activities Towards sustainability and globalisation of the Joint Programming Initiative on Neurodegenerative Diseases
Specific challenge: The EU Joint Programming Initiative on Neurodegenerative Diseases Research, in particular Alzheimer's (JPND), was established in 2009 as the pilot of the Member State-led Joint Programming Initiatives (JPI) to enable the participating EU Member States to work together on the challenge of age-related neurodegenerative diseases.
HORIZON 2020 Personalising health and care Understanding common mechanisms of diseases and their relevance in co-morbidities
Specific challenge:The development of new treatments is greatly facilitated by an improved understanding of the pathophysiology of diseases.
HORIZON 2020 Personalising health and care Health promotion and disease prevention: improved inter-sector co-operation for environment and health based interventions
Specific challenge: Better health promotion and disease prevention interventions can make a significant contribution to equitable health improvements and thus the sustainability of health and care systems.
HORIZON 2020 Personalising health and care Development of new diagnostic tools and technologies: in vivo medical imaging technologies
Specific challenge: The development of new diagnostics (more sensitive, robust and selective) for improved clinical practice demands the translation of multidisciplinary scientific and technological knowledge from diverse fields into clinical applications.
HORIZON 2020 Personalising health and care New therapies for rare diseases
Specific challenge:A considerable amount of knowledge has been generated by biomedical research in recent years, yet most of the 6000-8000 rare diseases are lacking therapies despite many diseases being life-threatening or chronically debilitating.
HORIZON 2020 PERSONALISING HEALTH AND CARE Tools and technologies for advanced therapies
Specific challenge:For their successful application, new therapies, such as gene or cell therapies, tissue engineering or regenerative medicine often require technological innovation in the form of development of specific component tools and techniques such as isolation and multiplication of a cell or development of a scaffold, delivery of the therapy to the patient and for following-up the effect of the therapy in the patient.
HORIZON 2020 Personalising health and care Establishing effectiveness of health care interventions in the paediatric population
Specific challenge:Knowledge about the overall benefit of healthcare interventions in the paediatric population is currently limited and may result in inappropriate interventions with acute or potentially lifelong impact on health and well-being.
HORIZON 2020 Personalising health and care Promoting mental wellbeing in the ageing population
Specific challenge:Health and care of the rapidly growing older population in Europe and elsewhere poses a number of specific challenges.
HORIZON 2020 Personalising health and care Piloting personalised medicine in health and care systems
Specificchallenge:Personalised medicine has the potential to respond to, amongst others, the increasing burden of chronic disease and the complexity of co-morbidities and in doing so contribute to the sustainability of health and care systems.
HORIZON 2020 Personalising health and care Piloting personalised medicine in health and care system PHC 9 – 2015: Vaccine development for poverty-related and neglected infectious diseases: HIV/AIDS
Specific challenge:Vaccines offer a safe and cost-effective way to protect large populations against infectious diseases, or at least to mitigate the clinical course of these diseases.
HORIZON 2020 PERSONALISING HEALTH AND CARE Clinical research on regenerative medicine
Specific challenge: Translating basic knowledge on regenerative medicine into the clinic is held up by the difficulty in undertaking ‘first in man’ studies.
HORIZON 2020 PERSONALISING HEALTH AND CARE New approaches to improve predictive human safety testing
Specific challenge:Current approaches assessing the safety of chemical substances in humans are expensive and time consuming, and may be of limited relevance as a predictor of adverse effects.
3rd Health Programme Innovation to prevent and manage chronic diseases
Objective: Put more emphasis on new approaches to prevention of major chronic diseases, including linking prevention to healthcare interventions, with an emphasis on groups most at risk.
3rd Health Programme Early diagnosis and screening of chronic diseases
Objective: Major chronic diseases, such as e.
3rd Health Programme Professional reintegration of people with chronic disease
Objective: An increasing number of people are unable to work due to chronic diseases.
3rd Health Programme Adherence, frailty, integrated care and multi-chronic conditions
Objective: The Commission has launched the European Innovation Partnerships within the Innovation Union, one of the flagship initiatives of the Europe 2020 strategy, with the objective of accelerating innovation to address a well-defined target within a grand societal challenge.
3rd Health Programme Statistical data for medicinal product pricing
Objective: Achieve a better coordination at the EU level in order to facilitate the control by the Member States of public budgets for medicinal products whilst avoiding/mitigating possible negative impacts on patient access to medicinal care.
3rd Health Programme Health monitoring and reporting system
Objective: EU data and health information system that supports monitoring, research and policy making in all areas of EU health policy.
3rd Health Programme Healthcare associated infection in long-term care
Objective: Enhance infection prevention and control in nursing homes and long-term care facilities in the EU, with the aim to prevent and contain the spread of antibiotic resistances in the long term.
3rd Health Programme Financial contribution to the functioning of non-governmental body
Objective: Operating grants can be awarded to non-governmental bodies, including networks, working at the EU level in any priority covered by the third Health Programme.
HORIZON 2020 Societal Challenges Health Co-ordination activities ERA-NET: Establishing synergies between the Joint Programming on Neurodegenerative Diseases Research and Horizon 2020
Proposals should coordinate national and regional programmes for research in the area of neurodegenerative diseases research by implementing a transnational call with EU co-funding resulting in grants to third parties, with a view to scale-up the implementation of the JPND Research Strategy.